Decapeptide-12 (Topical)

Decapeptide-12 200 mg (Topical Peptide)

This product is intended for laboratory research purposes only. To be used by laboratory professionals only.

Decapeptide-12 is a synthetic peptide made of twelve amino acids. It is used in research to study how melanin forms in the skin. This peptide is being tested for its effect on human tyrosinase, an enzyme that starts the melanin process. Early lab data shows that Decapeptide-12 may slow down how melanocytes make pigment.

This peptide is getting more attention in skincare-related studies focused on skin of color. Researchers are looking at how it might affect inflammation and how it interacts with cell membranes.

It is also studied for how it may reduce enzyme activity that leads to dark spots. These effects make it a useful tool for learning more about skin tone and how it changes over time.

Potential Benefits of Decapeptide-12 Topical Peptide

In clinical trial data, Decapeptide-12 has shown a measurable effect on melanin reduction. It may slow down the synthesis of pigment in melanocytes by interfering with tyrosinase expression.

Some in vivo studies suggest it works well in models simulating darker skin types, where inflammation and melanin overproduction are common. Because of these findings, it is being explored for its potential therapeutic role in hyperpigmentation research, though it remains strictly for research use only.

How Should Decapeptide-12 Topical Peptide Be Stored?

Decapeptide-12 should be stored in a cool, dry lab space between 2–8°C. If it is mixed with a liquid, it should be used quickly or kept frozen at –20°C. Peptides can break down if they go through too many freeze-thaw cycles, which could change how they work in lab tests.

Good storage helps make sure test results stay clear and consistent. Since this peptide is used to study melanin, inflammation, and transcription activity in skin cells, keeping it stable is key to getting solid data in research.

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References:

[1] Thawabteh AM, Jibreen A, Karaman D, Thawabteh A, Karaman R. Skin Pigmentation Types, Causes and Treatment-A Review. Molecules. 2023 Jun 18;28(12):4839.

[2] Kassim AT, Hussain M, Goldberg DJ. Open-label evaluation of the skin-brightening efficacy of a skin-brightening system using decapeptide-12. J Cosmet Laser Ther. 2012 Apr;14(2):117-21.

[3] Abu Ubeid A, Zhao L, Wang Y, Hantash BM. Short-sequence oligopeptides with inhibitory activity against mushroom and human tyrosinase. J Invest Dermatol. 2009 Sep;129(9):2242-9.

[4] Ochiai A, Tanaka S, Imai Y, Yoshida H, Kanaoka T, Tanaka T, Taniguchi M. New tyrosinase inhibitory decapeptide: Molecular insights into the role of tyrosine residues. J Biosci Bioeng. 2016 Jun;121(6):607-613.

Molecular formula: C65H90N18O17

Molecular weight: 1395.5 g/mol

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Lithuania Direct Peptides website: https://lithuania.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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