Buy VIP Peptide Lithuania
Buy VIP Peptide Lithuania, also known as Vasoactive Intestinal Peptide. It is a neuropeptide that plays a key role in several physiological processes, including aiding in smooth muscle relaxation, regulating inflammation, and promoting cardiovascular and gastrointestinal health.
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VIP Pre-Mixed Pen 2mg Peptide
Price range: £23.60 through £63.72 This product has multiple variants. The options may be chosen on the product page -
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BPC-157 VIP Nasal Stack
Price range: £41.13 through £73.26 This product has multiple variants. The options may be chosen on the product page -
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BPC-157 VIP Peptide Stack
Price range: £25.42 through £34.40 This product has multiple variants. The options may be chosen on the product page -
NEWThymosin Alpha-1 LL-37 VIP Peptide Stack
Original price was: £111.88.£100.69Current price is: £100.69. -
VIP Peptide Vial
Price range: £16.79 through £25.77 This product has multiple variants. The options may be chosen on the product page -
VIP Nasal Spray
Price range: £26.24 through £47.48 This product has multiple variants. The options may be chosen on the product page
What Is Vasoactive Intestinal Peptide?
Vasoactive Intestinal Peptide (VIP) is a small chain of 28 amino acid residues that acts as a chemical messenger in the body. It is extensively distributed throughout the central and peripheral nervous systems, where it functions as both a neurotransmitter and a neuromodulator.
It is classified as a neuropeptide, meaning it is produced by nerve cells and affects various bodily functions by binding to specific receptors called VPAC1, VPAC2, and PAC1. It has many important roles, such as helping to regulate blood flow by relaxing blood vessels (vasodilation), aiding in breathing by relaxing airways (bronchodilation), supporting smooth movement in the digestive system (gastrointestinal motility), and even influencing sleep-wake cycles (circadian rhythm).
Additionally, VIP has strong anti-inflammatory properties, which make it a focus of research for treating conditions like arthritis and sepsis where inflammation plays a key role.
VIP Peptide Mechanism Of Action
Vasoactive intestinal peptide (VIP) works by binding to specific cell surface receptors called VPAC1 and VPAC2. This activates G-proteins, which start a signal transduction process. The G-proteins then stimulate adenylate cyclase, an enzyme that converts ATP (adenosine triphosphate) into cAMP (cyclic adenosine monophosphate).
The rise in cAMP acts as a second messenger, activating protein kinase A (PKA). PKA then phosphorylates target proteins, leading to various effects like relaxing smooth muscles, reducing inflammation, and regulating immune functions. Through this process, VIP plays a key role in supporting normal physiological functions across multiple tissues.
Structure of VIP Peptide
Sequence: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-OH
Molecular Formula: C147H237N43O43S
Molecular Weight: 3326.8 g/mol
PubChem CID: 53314964
What Are The Research Benefits of VIP Peptide?
Anti-inflammatory: Research has shown it is a key anti-inflammatory mediator that reduces inflammation by suppressing pro-inflammatory cytokines (e.g., TNF-α, IL-6) and promoting anti-inflammatory cytokines (e.g., IL-10). It also inhibits inflammatory cell activation and protects tissue by maintaining epithelial barrier integrity, playing a vital role in immune balance and preventing chronic inflammation.
Studies show its potential as a treatment for various inflammatory conditions, including autoimmune diseases like rheumatoid arthritis and multiple sclerosis, inflammatory bowel diseases such as Crohn’s and ulcerative colitis, and respiratory conditions like asthma and COPD. Its anti-inflammatory properties highlight its versatility in managing chronic inflammation [1].
Blood Pressure: Studies reveal its critical role in promoting vasodilation by relaxing the smooth muscle cells in blood vessel walls. This process is triggered when it binds to specific receptors, increasing levels of cyclic adenosine monophosphate (cAMP). Elevated cAMP levels relax muscle fibers, causing blood vessels to widen and improving circulation.
This mechanism proves particularly beneficial in conditions like pulmonary hypertension, where enhanced blood flow helps alleviate strain on the heart and lungs, as well as Raynaud’s phenomenon, which restricts blood flow to extremities. Furthermore, it may aid in managing certain forms of ischemia, such as peripheral arterial disease, by boosting oxygen and nutrient delivery to affected tissues [2].
Brain Health: Research shows it exhibits significant neuroprotective effects, making it a promising molecule for addressing various neurological disorders. It acts by reducing neuronal inflammation, which is often a contributing factor in conditions such as multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease [3].
Additionally, it has been shown to enhance neuronal survival by promoting the release of neurotrophic factors and inhibiting apoptotic pathways. It also plays a role in modulating the immune response within the central nervous system, thereby mitigating damage caused by autoimmune processes. These combined effects highlight its potential as a therapeutic agent in preserving brain function and supporting neural repair mechanisms [4].
Gut Health: Research shows it plays a key role in supporting digestive health by regulating important processes in the gastrointestinal system. It helps relax the smooth muscles in the digestive tract, improving motility and reducing the risk of issues like spasms and irritable bowel syndrome (IBS).
It also stimulates the release of water and electrolytes into the intestine, keeping the lining hydrated and aiding healthy digestion. Its anti-inflammatory properties help maintain intestinal health and lower the risk of inflammation-related conditions like Crohn’s disease. Additionally, it regulates gastric acid secretion, promoting balance in the stomach and overall digestive stability [5].
Heart Health: Research shows that it has significant benefits for cardiovascular health due to its ability to act as a powerful vasodilator. It relaxes the smooth muscles in blood vessels, reducing resistance and improving blood flow. This helps deliver oxygen and nutrients more effectively to tissues throughout the body.
It also helps regulate heart rate and influences how cardiac tissues contract, which could make it useful for treating conditions like heart failure. Additionally, its anti-inflammatory and anti-apoptotic properties may protect the heart from damage caused by oxidative stress and inflammation, supporting overall heart health [6].
Metabolic Health: Research highlights its role in supporting metabolic health by regulating glucose and lipid metabolism, improving insulin sensitivity, and reducing inflammation. It may help manage metabolic disorders like type 2 diabetes and support healthy weight by influencing appetite and energy balance. Additionally, it aids placentation and fetal development, improving glucose and fatty acid metabolism while reducing oxidative stress, potentially addressing pregnancy complications like preeclampsia and fetal growth restriction [7].
Circadium Rhythm: Research shows that it plays a key role in regulating the circadian rhythm, which controls the body’s internal biological clock. It helps maintain the synchronization of neuronal activity within the brain’s master clock, a complex network of nerve cells known as the suprachiasmatic nucleus (SCN). By influencing cell signalling in the SCN, the peptide helps maintain a stable daily cycle of bodily processes. Disrupted VIP signalling can affect circadian rhythms, impacting sleep, hormone release, and overall health. Its role in coordinating the SCN highlights its importance in keeping the biological clock healthy [8].
Buy VIP Peptide Vial Lithuania for laboratory research use today!
Buy VIP Peptide BPC-157 Nasal Stack
Buy VIP Peptide and BPC-157 Nasal Stack Lithuania for research purposes and enjoy a convenient, cost-effective solution. Available in 15 ml and 30 ml options, this stack includes one VIP nasal spray and one BPC-157 nasal spray, offering a 10% discount compared to buying them separately.
Nasal administration may enhance absorption, delivering faster, more targeted effects. This combination shows potential for supporting inflammation relief, immune system health, and accelerated healing.
Buy VIP Peptide Pre-Mixed Pen
Buy VIP Pre-Mixed 2 mg Pen Lithuania for in-vivo and in-vitro laboratory studies. It is a specialised delivery system designed to provide precise and convenient administration of Vasoactive Intestinal Peptide. It simplifies the process of measuring and dosing, ensuring consistency and ease of use.
Pre-Mixed Cartridge Kits include a premixed cartridge with your chosen peptide and bacteriostatic water, a pen, carry case, and needle tips. Single Mixed Cartridges (1, 2, or 3) include premixed cartridges and needle tips, but no kit. Save 10% when purchasing 3 cartridges.
Frequently Asked Questions (FAQs) about VIP Peptide
Can Vasoactive Intestinal Peptide help treat IBS?
Studies show promise as a treatment for irritable bowel syndrome (IBS) due to its role in regulating intestinal motility, secretion, and immune responses. Early Lithuania research suggests it may help restore normal gut function and reduce hypersensitivity. However, more clinical studies are needed to confirm its safety, effectiveness, and optimal delivery methods.
Does VIP Peptide have any side effects?
While it shows promise for therapeutic use, potential adverse effects should be considered. Early Lithuania studies report flushing, mild nausea, dizziness and temporary drops in blood pressure, which are usually short-lived and manageable. However, further research is needed to investigate it’s long-term safety. Responses may vary, so consult a healthcare professional before use.
Is VIP Peptide legal?
The legality depends on its intended use and the region in question. In the United States, the Food and Drug Administration (FDA) regulates peptides for medical purposes. It is not currently approved for widespread clinical use or over-the-counter purchase. However, it is possible to buy vip peptide for research purposes under strict regulations. It is essential to exercise caution and adhere to applicable laws and regulations. For clarity on its legal status, always seek guidance from a qualified legal or healthcare professional.
How does Vasoactive Intestinal Peptide boost the immune system?
It helps balance the immune response by reducing inflammation and preventing excessive activity that can lead to autoimmune conditions. It promotes anti-inflammatory cytokines while inhibiting pro-inflammatory ones, maintaining a healthier immune balance. It also supports regulatory T cells, essential for controlling inflammation and self-tolerance. These qualities highlight its potential for managing immune-related disorders.
Buy VIP Peptide Lithuania for scientific research only from Direct Peptides.
Summary of Research Applications
- Enhances cognitive function.
- Protects against neurological conditions.
- Promotes immune regulation.
- Potential treatment for inflammatory diseases.
- Supports cellular repair.
- Helps lower blood pressure.
- Treatment for cardiac fibrosis.
- Protects the digestive tract from gastrointestinal disorders.
- It improves motility, stimulating electrolytes and secretion of water.
Buy VIP Peptide Lithuania for research today.
VIP Peptide Quality Assured
Buy VIP peptide with 99% purity from Direct Peptides, ideal for supporting scientific research on vasodilation, bronchodilation, gut motility, circadian rhythms and inflammation.
Our peptides have been tested by third-party laboratories to ensure the highest purity, potency, and consistency in every batch.
At Direct Peptides, we know how important reliable results are for scientific research. That’s why we provide fast and efficient worldwide shipping, ensuring your peptides and research chemicals arrive safely.
References For Further Reading
[1] Carmen Martínez, Yasmina Juarranz, Irene Gutiérrez-Cañas, Mar Carrión, Selene Pérez-García, et al (2019) A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases – International Journal of Molecular Sciences, 2019 Dec 20, Volume 21 (Issue 1), Page 65.
[2] R J Henning and D R Sawmiller (2001) Vasoactive intestinal peptide: cardiovascular effects – Cardiovascular Research, 2001 Jan, Volume 49 (Issue 1), Pages 27-37.
[3] Donald R Staines, Ekua W Brenu, and Sonya Marshall-Gradisnik (2009) Postulated vasoactive neuropeptide immunopathology affecting the blood-brain/blood-spinal barrier in certain neuropsychiatric fatigue-related conditions: A role for phosphodiesterase inhibitors in treatment? – Neuropsychiatric Disease and Treatment, 2009, Volume 5, Pages 81-9.
[4] Jie Yang, Chang Yang, YuanBo Yang, Ning Jia, and QinRu Sun (2022) Protection of Vasoactive Intestinal Peptide on the Blood-Brain Barrier Dysfunction Induced by Focal Cerebral Ischemia in Rats – Journal of Stroke and Cerebrovascular Diseases, Volume 31, Issue 4, April 2022, 106160.
[5] Xiaopeng Bai, Giada De Palma, Elisa Boschetti, Yuichiro Nishiharo, Jun Lu, et al (2024) Vasoactive Intestinal Polypeptide Plays a Key Role in the Microbial-Neuroimmune Control of Intestinal Motility – Cellular & Molecular Gastroenterology Hepatology, 2024, Volume 17 (Issue 3), Pages 383-398.
[6] Raquel Benitez, Virginia Delgado-Maroto, Marta Caro, Irene Forte-Lago, Mario Duran-Prado, et al (2018) Vasoactive Intestinal Peptide Ameliorates Acute Myocarditis and Atherosclerosis by Regulating Inflammatory and Autoimmune Responses – The Journal of Immunology, 01 June 2018, Volume 200 (Issue 11), Pages 3697-3710.
[7] Fátima Merech, Brenda Lara, Daiana Rios, Daniel Paparini, Rosanna Ramhorst, et al (2025) Vasoactive intestinal peptide induces metabolic rewiring of human-derived cytotrophoblast cells to promote cell migration – Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, Volume 1872, Issue 2, February 2025, 119886.
[8] Ryan Hamnett, Priya Crosby, Johanna E. Chesham & Michael H. Hastings (2019) Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling – Nature Communications, volume 10, Article number: 542 (2019).
Why Choose Direct Peptides Lithuania?
Buy VIP Peptide Lithuania today from Direct Peptides, your trusted source for research-grade peptides. We offer a wide range of VIP formulations to meet your research needs, including 2 mg peptide vials, peptide stacks for potential synergistic effects, peptide nasal sprays in 15ml and 30ml bottles, and 2 mg pre-mixed peptide pens for added convenience. Whatever your research project requires, we have the precise formulations to support your work.
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Lithuania Direct Peptides website: https://lithuania.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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