Buy Tesamorelin Peptide Lithuania
Tesamorelin is a synthetic analogue of growth hormone-releasing factor, designed to reduce excess abdominal fat in individuals affected by HIV-associated lipodystrophy.
Shop our Full Range of Tesamorelin Peptides
-
Sale!
Tesamorelin & Ipamorelin Peptide Stack
Price range: £32.87 through £41.85 This product has multiple variants. The options may be chosen on the product page -
NEWTesamorelin Sermorelin
Price range: £37.78 through £46.76 This product has multiple variants. The options may be chosen on the product page -
Sale!
Tesamorelin Ipamorelin CJC-1295 DAC
Price range: £54.64 through £62.73 This product has multiple variants. The options may be chosen on the product page -
Tesamorelin Nasal Spray
Price range: £31.49 through £57.98 This product has multiple variants. The options may be chosen on the product page -
Sale!
Ipamorelin Tesamorelin CJC-1295 no DAC
Price range: £49.73 through £58.71 This product has multiple variants. The options may be chosen on the product page -
Sale!
Tesamorelin Pre-Mixed Pen 2mg Peptide
Price range: £28.34 through £76.52 This product has multiple variants. The options may be chosen on the product page -
BULK BUY
Tesamorelin Peptide Vial
Price range: £24.14 through £303.59 This product has multiple variants. The options may be chosen on the product page
What Is Tesamorelin?
Tesamorelin is a synthetic peptide designed to mimic growth hormone-releasing hormone (GHRH). Consisting of 44 amino acids, it works by stimulating the GHRH receptors at the base of the pituitary gland to produce and release growth hormone (hGH). This increase in growth hormone helps break down visceral fat, making it an important treatment for managing abnormal fat distribution.
It is especially useful for patients with HIV-associated lipodystrophy, a condition caused by antiretroviral therapy that can lead to physical and metabolic problems. Lithuania Studies show that Tesamorelin effectively reduces visceral fat while maintaining a good safety profile, providing significant benefits for patients facing this condition.
Tesamorelin Mechanism Of Action
Tesamorelin works by mimicking the action of endogenous growth hormone-releasing hormone (GHRH), thereby stimulating the pituitary gland to release growth hormone (GH). Once released, human growth hormone interacts with target tissues, promoting the production of insulin-like growth factor-1 (IGF-1) primarily in the liver. This increase in IGF-1 levels is critical, as it enhances lipid mobilisation and facilitates the breakdown of triglycerides stored in visceral adipose tissue.
By specifically targeting these fat deposits, Tesamorelin reduces the accumulation of visceral fat without significantly affecting subcutaneous fat or lean body mass. Its mechanism of action ensures a focused treatment effect, which is particularly beneficial in addressing metabolic abnormalities without broader systemic disruption.
Structure of Tesamorelin
Sequence: trans-hexenoyl-acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn- Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-LeuGln-Asp-Ile-Met-Ser-Arg-Gln- Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
Molecular Formula: C221H366N72O67S
Molecular Weight: 5136 g/mol
PubChem CID: 146681838
What Are The Research Benefits of Tesamorelin?
Effects on Lipodystrophy: Lithuania Research has shown promise in addressing the effects of lipodystrophy. Lipodystrophy causes an uneven distribution of body fat, leading to fat loss (lipoatrophy) in some areas and fat buildup (lipohypertrophy) in others. It is often associated with metabolic problems like insulin resistance and high cholesterol.
Research has demonstrated that individuals with lipodystrophy tend to exhibit reduced growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels. Two phase III studies involving 806 participants highlighted it’s impact on lipid metabolism over a 26-week period, with a subsequent 26-week extension. Results indicated a 15.4% reduction in visceral adipose tissue and improved triglyceride and cholesterol levels among the peptide users compared to the placebo group [1].
Visceral Fat Reduction: Also known as visceral obesity, is a condition characterised by the accumulation of excess fat around internal organs. This type of fat is prevalent in individuals with lipodystrophy and is strongly associated with a range of metabolic complications, including insulin resistance, atherosclerosis, elevated LDL cholesterol levels, and hyperuricemia. It has been shown to have a significant impact on reducing visceral fat.
Lithuania Clinical trials indicate that it can effectively decrease visceral adipose tissue by up to 25% in lipodystrophy models. This reduction in visceral fat not only supports a healthier metabolic profile but also contributes to mitigating the risks linked to related metabolic disorders, further emphasising its therapeutic potential [2].
Immunodeficient Fat Fractions: A study examined the effects of the peptide on non-alcoholic fatty liver disease (NAFLD) in HIV-positive individuals. Over 12 months, 61 participants with high hepatic fat fraction (HFF) received either Tesamorelin or a placebo. Results showed 35% of peptide-treated participants had a significant HFF reduction, compared to only 4% in the placebo group, with no impact on glucose levels [3].
Insulin Sensitivity: A 12-week randomized trial studied the effects of the peptide on insulin sensitivity in 53 participants with Type II diabetes. Participants were divided into three groups, receiving either a high or low dose of the peptide or a placebo. Measurements of fasting glucose, glycosylated hemoglobin, and diabetes control showed no significant improvements across all groups [4].
Another study examined its effects on GH secretion and insulin sensitivity in 13 healthy men. Two weeks of treatment increased GH and IGF-I levels without affecting fasting glucose or insulin sensitivity, suggesting enhanced GH secretion without metabolic impairment [5].
Effects on Muscle Tissue: A study evaluated the peptide’s effects on muscle tissue using CT scans. Results suggested that it may improve muscle density and volume, particularly in the rectus abdominis, psoas major, and paraspinal muscles. These changes included increased density, size, or reduced fat, with significant differences compared to a placebo group [6].
Cognition: A clinical study investigated it’s effect on neurological functioning in 100 immunodeficient participants with mild cognitive impairment, aged 40+. The trial involved daily peptide treatment for 6 months, a 6-month break, and another 6 months of treatment. Neurocognitive performance is being measured using the Global Deficit Score (GDS) at 6 and 12 months. Final results are pending publication [7].
Buy Tesamorelin Lithuania for research purposes online today!
Buy Tesamorelin Ipamorelin CJC no DAC Stack
Buy Tesamorelin, Ipamorelin and CJC-1295 no DAC peptide stack Lithuania for laboratory use from Direct Peptides, a trusted supplier of peptides. It aims to target areas such as growth hormone regulation, fat reduction, and overall metabolic enhancements. Ensure vials are at room temperature before mixing with bacteriostatic water.
Buy Tesamorelin Peptide Nasal Spray
Buy Tesamorelin nasal spray Lithuania for research use. A convenient formulation available in 15ml and 30ml variants, offering a non-invasive an alternative to subcutaneous injections. The nasal spray’s ease of use improves patient compliance while ensuring consistent dosing.
Frequently Asked Questions (FAQs) about Tesamorelin
How is Tesamorelin administered?
It is administered as a subcutaneous injection, typically once daily. It is important to follow the dosage instructions provided by healthcare professionals to ensure optimal results.
What are the potential side effects of Tesamorelin?
Common side effects include injection site reactions such as mild irritation, redness and inflammation. Other adverse effects have included joint pain, swelling, and muscle aches. In rare cases, individuals might experience allergic reactions or symptoms of carpal tunnel syndrome. If side effects persist or worsen, it’s important to seek medical attention.
Can Tesamorelin improve cognitive function?
Current Lithuania research is exploring whether it has benefits for cognitive function, especially in individuals with mild cognitive impairment. While early findings are promising, conclusive results are still pending further studies.
Are Tesamorelin syringes safe for everyone?
They are not recommended for individuals with a history of cancer, active malignancy, or those who are pregnant or breastfeeding. It is essential to discuss your medical history and conditions with your doctor before starting any treatment.
Do I need a prescription for a Tesamorelin injection?
Yes, it is a prescription medication and should only be used under the guidance of a licensed healthcare provider.
Is it legal to buy Tesamorelin?
It is an FDA approved synthetic hormone used to treat HIV-associated lipodystrophy. Its legal use is limited to this condition, and it is not authorised for weight loss or anti-aging. Off-label use can pose legal and health risks, highlighting the importance of medical guidance.
Buy Tesamorelin Pre-Mixed Pen Lithuania for laboratory research purposes from Direct Peptides.
Pre-Mixed Cartridge Kits include a peptide cartridge, pen, carry case, and needle tips. Single Cartridges (available in sets of 1, 2, or 3) come with needle tips but no kit. Save 10% when purchasing 3 cartridges.
Summary of Research Applications
- Treatment of lypodystrophy.
- Weight loss.
- Reduced visceral fat around the abdominal.
- Potential cognitive enhancement.
- Improved muscle tissue.
- Lowers cholesterol levels.
- Improves insulin sensitivity.
Tesamorelin Peptide Quality Assured
Buy Tesamorelin peptide Lithuania with 99% purity from Direct Peptides, designed to support your scientific research on growth hormone and its numerous benefits.
Our Lithuania team of experts is dedicated to providing you with the highest quality products and customer service, ensuring that your research is successful and accurate.
References For Further Reading
[1] Julian Falutz, Jean-Claude Mamputu, Diane Potvin, Graeme Moyle, et al (2010) Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data – Journal of Clinical Endocrinology & Metabolism, 2010 Sep, Volume 95 (Issue 9), Pages 4291-304.
[2] T Sivakumar, Oj Mechanic, D A Fehmie, and Bt Paul (2011) Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review of placebo-controlled trials – HIV Medicine, 2011 Sep, Volume 12 (Issue 8), Pages 453-62.
[3] Takara L Stanley, Lindsay T Fourman, Meghan N Feldpausch, Julia Purdy, et al (2019) Effects of Tesamorelin on Nonalcoholic Fatty Liver Disease in HIV: A Randomized, Double-Blind, Multicenter Trial – The Lancet Journal – HIV, Volume 6, Issue 12e821-e830, December 2019.
[4] David R Clemmons, Sam Miller, and Jean-Claude Mamputu (2017) Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial – PLoS One, 2017 Jun 15, Volume 12 (Issue 6), Page e0179538.
[5] Takara L Stanley, Cindy Y Chen, Karen L Branch, Hideo Makimura, and Steven K Grinspoon (2010) Effects of a Growth Hormone-Releasing Hormone Analog on Endogenous GH Pulsatility and Insulin Sensitivity in Healthy Men – Journal of Clinical Endocrinology & Metabolism, 2010 Oct 13, Volume 96 (Issue 1), Pages 150–158.
[6] Stefan Adrian, Ann Scherzinger, Abanti Sanyal, Jordan E Lake, et al (2020) The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV – The Journal of Frailty & Aging, Volume 8, Issue 3, July 2019, Pages 154-159.
[7] Ronald J Ellis , Florin Vaida , Keren Hu , Michael Dube , Brook Henry, et al (2025) Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesity – The Journal of Infectious Diseases, jiaf012, 15 January 2025.
Why Choose Direct Peptides Lithuania?
Buy Tesamorelin Lithuania today and enjoy premium quality with Direct Peptides, your trusted source for peptides. We offer a variety of formulations to meet your research needs, including 2mg, 5mg, and 10mg vials, peptide stacks, 15ml and 30ml nasal sprays, and pre-mixed peptide pens. Our products are designed to deliver precise, high-quality results for your projects.
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Lithuania Direct Peptides website: https://lithuania.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
Related Posts
Tesamorelin for Muscle Growth: Key Research Benefits
Originally developed for HIV-associated lipodystrophy, it is gaining attention for its potential to improve muscle growth, reduce visceral fat, and enhance body composition. This blog explores how it stimulates natural growth hormone production, to support muscle development and fat loss.
Tesamorelin vs Sermorelin: Unlocking Research Potential
These peptides are transforming research in metabolic health and growth hormone regulation. This blog explores their individual strengths, their roles in fat reduction, muscle building, and anti-aging, and the potential benefits of combining them.