Pentapeptide-18 (Topical)

Buy Pentapeptide-18 200mg (Topical)

This product is intended for research purposes only. To be used by trained professionals only.

Pentapeptide-18 also known as Leuphasyl is a synthetic peptide used strictly in controlled lab-based studies. Often compared to argireline, another wrinkle-focused peptide, it works through a slightly different process.

It mimics natural brain messengers called enkephalins. These chemical signals help ease the nerve activity that causes muscles in the face to contract. With less tension at the surface, fewer expression lines may appear. That’s the idea and in lab testing, results so far are encouraging. [1]

Researchers are looking into its potential as a gentler alternative to more invasive treatments like Botox. While it’s not made for skincare products used at home, it’s being closely examined for what it can offer in the future of cosmetic science. [2]

Potential Benefits of Pentapeptide-18

In lab-based skin care research, Pentapeptide-18 has shown signs of helping to relax the facial muscles that deepen with age particularly around the eyes, forehead, and mouth. This softening effect could contribute to smoother texture and a firmer look over time. [3]

Some believe it might even help delay new wrinkle formation. By reducing repetitive stress in high-motion areas, the skin gets a chance to settle.

It may also work well alongside other common ingredients, like salicylic acid, moisturizers, or even collagen-boosting compounds. While it doesn’t moisturize or exfoliate on its own, it may amplify results when combined with those that do. [4]

Though not approved for personal use, its ability to reduce wrinkle depth in controlled settings keeps it a topic of serious interest in anti-aging research.

How Should Pentapeptide-18 Be Stored?

To maintain its quality during study, Pentapeptide-18 should be kept in a cool, dry place ideally under 4°C (39°F). For extended storage, freezing it at -20°C helps preserve its stability. Keep it sealed in its original container, away from heat and sunlight.

Light and warmth can break it down. Repeated thawing and freezing? Best avoided, as it may weaken its consistency over time.

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References

[1] Pintea A, Manea A, Pintea C, Vlad RA, Bîrsan M, Antonoaea P, Rédai EM, Ciurba A. Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review. Biomolecules. 2025 Jan 9;15(1):88.

[2] Pawłowska M, Marzec M, Jankowiak W, Nowak I. Solid Lipid Nanoparticles Incorporated with Retinol and Pentapeptide-18-Optimization, Characterization, and Cosmetic Application. Int J Mol Sci. 2024 Sep 19;25(18):10078.

[3] Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020 Oct 30;8:572923.

[4] Waszkielewicz, A.M.; Mirosław, K. Peptides and Their Mechanisms of Action in the Skin. Appl. Sci. 2024, 14, 11495.

Molecular Formula: C29H39N5O7

Molecular Weight: 569.6 g/mol

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Lithuania Direct Peptides website: https://lithuania.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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